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PUID: 58 || PLAB 2 Mock :: Dermatology: Psoriasis

Updated: Aug 16

Summary

A PLAB 2 station involving the assessment, diagnosis, and management of a patient presenting with skin lesions later identified as psoriasis. The candidate must balance efficient history-taking with timely transition to examination and management, recognising key features, addressing patient concerns, identifying risk factors, and providing evidence-based treatment options.



Key Points


Dermatology – Psoriasis

  • Definition: Chronic autoimmune skin condition with rapid skin turnover, producing thick, scaly plaques.

  • Typical Sites: Extensor surfaces (elbows, knees), scalp, lower back.

  • Classic Signs:

    • Auspitz sign – punctate bleeding when scales are removed.

    • Koebner phenomenon – lesions appearing at trauma sites.

  • Risk Factors:

    • Non-modifiable: Family history, autoimmune tendency.

    • Modifiable: Stress, smoking, alcohol, certain drugs (β-blockers, lithium, antimalarials), infections, obesity, vitamin D deficiency, excessive UV exposure.


Psychosocial Aspects

  • Misconception about contagion.

  • Impact on self-esteem, daily life, and employment.

  • Stress both as a trigger and consequence of disease.



Important Considerations

  • Psoriasis is treatable but not curable.

  • Identify systemic involvement (psoriatic arthritis, uveitis, nail disease).

  • Always address patient concerns directly (use ICE – Ideas, Concerns, Expectations).

  • Avoid excessive time in history once working diagnosis is reached – marks shift to management.



Diagnostic Approach

  1. Initial Data Gathering

    • Onset, duration, progression of rash.

    • Location, distribution, spread to other areas.

    • Associated symptoms: itching, pain, bleeding, systemic symptoms.

    • Previous episodes, treatments tried, and responses.

    • Exposure/contact history (to rule out contagious causes).

  2. Risk Factor Screening

    • Family history of psoriasis or autoimmune disease.

    • Modifiable triggers: stress, smoking, alcohol, drugs, recent infections, new skincare products.

  3. Complication Check

    • Joint pain/swelling, morning stiffness (psoriatic arthritis).

    • Eye redness/pain (uveitis).

    • Nail pitting, onycholysis.

  4. Examination

    • Lesion morphology, size, distribution.

    • Check scalp, nails, joints, and eyes.

    • Assess severity and body surface area involvement.



Management


First-line GP Management

  • Education & Reassurance: Non-contagious nature, chronic course, treatment aims.

  • Skin Care:

    • Liberal emollients – apply before other treatments, leave 30 mins.

    • Potent topical corticosteroids – daily for up to 8 weeks (4 weeks for very potent), followed by steroid-free break.

    • Vitamin D analogues – use on ≤30% body surface area to avoid hypercalcaemia, rotate application sites, separate from steroid application to prevent inactivation.

    • Salicylic acid for thick scale removal.


Lifestyle Modifications

  • Stress reduction strategies (exercise, mindfulness, support groups).

  • Smoking cessation and alcohol moderation.

  • Weight management.

  • Maintain a trigger diary.


Safety Netting

  • Seek prompt review if:

    • Signs of infection in lesions.

    • New joint pain/swelling or morning stiffness.

    • Eye pain/redness.

    • Sudden worsening of skin symptoms.


Referral Criteria

  • Failure of primary care treatment.

  • Severe or extensive disease.

  • Systemic involvement.

  • Consider phototherapy or systemic therapy under dermatology.



Communication Skills

  • Start with open-ended questions to elicit patient’s perspective.

  • Avoid overusing rehearsed phrases; speak naturally.

  • Empathise without false emotion.

  • Check patient understanding after explanations.

  • Involve patient in decision-making and agree on management plan.


Ethical Considerations

  • Respect dignity, privacy, and autonomy.

  • Maintain professional boundaries.

  • Provide information in accessible, jargon-free language.

  • Follow Good Medical Practice by supporting self-care and providing safe, evidence-based treatment.


Additional Resources

  • NICE Clinical Knowledge Summary: Psoriasis.

  • BAD (British Association of Dermatologists) patient information leaflets.

  • GMC Good Medical Practice (2024) – Domains 1 & 2.

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