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MSRA High-Yield MCQs: Pre-eclampsia, Eclampsia & HELLP Syndrome

Updated: Jul 4

  1. Which of the following would most warrant urgent delivery in a woman with pre-eclampsia?

Choose one of the options

  • BP 140/90 mmHg

  • 1+ protein on dipstick

  • Severe headache and visual disturbance

  • BMI >35


Answer: C. Severe headache and visual disturbance

Suggests severe disease → urgent stabilisation and likely delivery.

  1. A 31-year-old woman at 37+2 weeks gestation presents with BP 150/100 mmHg and 2+ proteinuria. She has no symptoms and normal bloods. What is the most appropriate next step?

Choose one of the options

  • Continue monitoring

  • Start oral labetalol

  • Administer IV magnesium sulfate

  • Plan delivery


Answer: D. Plan delivery

Pre-eclampsia at ≥37 weeks without severe features → offer delivery.

  1. Which of the following is not a known complication of pre-eclampsia?

Choose one of the options

  • Placental abruption

  • Pulmonary embolism

  • Acute kidney injury

  • Fetal growth restriction


Answer: B. Pulmonary embolism

PE is not a direct complication of pre-eclampsia; the others are.

  1. A patient on magnesium sulfate develops absent deep tendon reflexes and bradypnea. What is the most appropriate next step?

Choose one of the options

  • Increase magnesium infusion

  • Administer calcium gluconate

  • Start IV hydralazine

  • Perform emergency C-section


Answer: B. Administer calcium gluconate

Classic magnesium toxicity → treat with 10 mL 10% calcium gluconate IV.

  1. Pre-eclampsia occurring before 20 weeks is most suggestive of:

Choose one of the options

  • Multiple pregnancy

  • Uncontrolled Type 1 diabetes

  • Triploidy

  • Gestational hypertension


Answer: C. Triploidy

Atypical early-onset pre-eclampsia <20 wks → think molar pregnancy or triploidy.

  1. A woman with chronic hypertension presents at 32 weeks with worsening proteinuria and RUQ pain. Diagnosis?

Choose one of the options

  • Gestational hypertension

  • Normal progression of chronic HTN

  • HELLP syndrome

  • Superimposed pre-eclampsia


Answer: D. Superimposed pre-eclampsia

Chronic HTN + new proteinuria/symptoms = superimposed PE.

  1. Which medication is contraindicated for hypertension in pregnancy?

Choose one of the options

  • Methyldopa

  • Labetalol

  • Nifedipine

  • Enalapril


Answer: D. Enalapril

ACE inhibitors are teratogenic → contraindicated in pregnancy.

  1. According to NICE, what is the target BP for pregnant women with pre-eclampsia but no end-organ damage?

Choose one of the options

  • <160/110

  • <140/90

  • <130/80

  • <150/100


 Answer: D. <150/100

NICE: target <150/100 unless organ damage → then <140/90.

  1. Which of the following is a classic clue for HELLP syndrome?

Choose one of the options

  • Seizures

  • Hypoglycaemia

  • Thrombocytosis

  • RUQ pain with ↑AST, ↓platelets, schistocytes


Answer: D. RUQ pain with ↑AST, ↓platelets, schistocytes

Triad = haemolysis, ↑LFTs, ↓platelets.

  1. At what gestation should delivery be offered in women with pre-eclampsia without severe features?

Choose one of the options

  • 32 weeks

  • 34 weeks

  • 36 weeks

  • 37 weeks

Answer: D. 37 weeks

≥37 weeks = plan delivery even if asymptomatic.

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