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High-Yield Skin Cancer MCQs for PLAB 2 / UKMLA

1. A 68-year-old man presents with a slow-growing lesion on the nose. It is pearly with visible blood vessels. Most likely diagnosis?

  • A. Malignant melanoma

  • B. Squamous cell carcinoma

  • C. Basal cell carcinoma

  • D. Actinic keratosis



2. A chronic ulcer on the lower lip that is indurated and bleeds easily.

  • A. BCC

  • B. SCC

  • C. Melanoma

  • D. Psoriasis



3. Which skin cancer has the highest metastatic potential?

  • A. BCC

  • B. SCC

  • C. Melanoma

  • D. Actinic keratosis



4. Which is a precursor to SCC?

  • A. Melanocytic nevus

  • B. Actinic keratosis

  • C. Lipoma

  • D. Hemangioma



5. “Rodent ulcer” refers to:

  • A. Melanoma

  • B. SCC

  • C. BCC

  • D. Fungal infection



6. A dome-shaped lesion with central keratin plug growing rapidly.

  • A. SCC

  • B. BCC

  • C. Keratoacanthoma

  • D. Melanoma



7. Which suggests SCC over BCC?

  • A. Pearly edge

  • B. Slow growth

  • C. Pain + lymphadenopathy

  • D. Telangiectasia



8. Which is most common?

  • A. Melanoma

  • B. SCC

  • C. BCC

  • D. Merkel cell carcinoma



9. Which is most specific for melanoma?

  • A. Smooth border

  • B. Uniform colour

  • C. Evolution

  • D. Crusting



10. Which UV pattern is most associated with melanoma?

  • A. Chronic daily exposure

  • B. Occupational exposure

  • C. Intermittent intense exposure

  • D. Indoor lighting


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