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Undescended Testis & Enuresis in Children: MSRA High-Yield Guide

  1. A 6-week-old boy is reviewed at his routine baby check. His left testis is not palpable in the scrotum, but no hypospadias is noted. What is the most appropriate next step?


Choose the correct answer

  • A) Urgent referral to paediatrics within 24 hours

  • B) Refer to paediatric surgery now

  • C) Re-examine at 4-5 months

  • D) Arrange urgent karyotyping

Answer: C) Re-examine at 4-5 months

Explanation:

  • If unilateral undescended testis at 6-8 week check → re-examine at 4-5 months.

  • If still undescended by 6 months → refer for orchidopexy.

Hormonal therapy is not recommended



  1. A 2-month-old male infant has bilateral non-palpable testes and hypospadias. What is the next best step?

Choose the correct answer

  • A) Arrange orchidopexy at 12 months

  • B) Monitor until 6 months

  • C) Urgent referral to paediatrics within 24 hours

  • D) Start testosterone therapy

Answer: C) Urgent referral to paediatrics within 24 hours

Explanation:

Bilateral undescended testes or associated hypospadias → suspect DSD → urgent endocrine/genetic evaluation within 24 hours.




  1. A 5-year-old boy presents with testicular pain and a non-retractile undescended testis. What is the most serious complication to consider?

Choose the correct answer

  • A) Infertility

  • B) Testicular torsion

  • C) Inguinal hernia

  • D) Testicular atrophy

Answer: B) Testicular torsion

Explanation:

While infertility and malignancy are long-term risks, torsion is an acute emergency with an increased risk in undescended testes.




  1. Which of the following statements about cryptorchidism is FALSE?

Choose the correct answer

  • A) It increases the risk of testicular cancer

  • B) Orchidopexy reduces infertility risk

  • C) Hormonal therapy with hCG is first-line in the UK

  • D) It is more common in preterm infants

Answer: C) Hormonal therapy with hCG is first-line in the UK

Explanation:

Hormonal therapy is not recommended in the UK; surgical orchidopexy is the definitive treatment.




  1. At what age should orchidopexy ideally be performed for an undescended testis?

Choose the correct answer

  • A) Before 3 months

  • B) Between 6-12 months

  • C) At 18 months

  • D) Between 2-4 years

Answer: B) Between 6-12 months

Explanation:

Best outcomes (fertility and cancer risk reduction) if done by 12 months, and no later than 18 months.




  1. Which of the following is a risk factor for cryptorchidism?

Choose the correct answer

  • A) Large for gestational age

  • B) Hypertension in pregnancy

  • C) Prematurity

  • D) Maternal diabetes

Answer: C) Prematurity

Explanation:

Prematurity, low birth weight, small for gestational age, family history, genetic abnormalities (e.g. hypospadias) are risk factors.



  1. A 6-year-old boy is brought to the GP due to bedwetting 4 nights a week. He has no daytime urinary symptoms. The parents want long-term treatment. What is the first-line management?

Choose the correct answer

  • A) Reassurance

  • B) Desmopressin

  • C) Enuresis alarm

  • D) Oxybutynin

Answer: C) Enuresis alarm

Explanation:

  • ≥5 years + frequent bedwetting (>2x/week) + no daytime symptoms → Enuresis alarm (first-line for long-term control).

Desmopressin is for short-term control or >7 years if alarm unsuitable.




  1. A 4-year-old girl wets the bed twice a week. There are no daytime symptoms. What is the next step?

Choose the correct answer

  • A) Start desmopressin

  • B) Start enuresis alarm

  • C) Refer to paediatrics

  • D) Reassure parents

Answer: D) Reassure parents

Explanation:

<5 years = reassurance only as continence may be achieved with age.




  1. A 9-year-old boy develops new-onset bedwetting after being dry for 2 years. His mother reports he is drinking a lot and has lost weight recently. What is the most appropriate next step?

Choose the correct answer

  • A) Start enuresis alarm

  • B) Start desmopressin

  • C) Reassure

  • D) Check urine for glucose

Answer: D) Check urine for glucose

Explanation:

Secondary enuresis + polyuria + polydipsia + weight loss → suspect Diabetes Mellitus → urgent glucose check.




  1. Which of the following is NOT a cause of secondary enuresis?

Choose the correct answer

  • A) Emotional upset

  • B) UTI

  • C) Constipation

  • D) Sleep arousal difficulty

Answer: D) Sleep arousal difficulty

Explanation:

Sleep arousal difficulty = mechanism for primary nocturnal enuresis, not a cause of secondary (which is due to new pathology or emotional stress after being dry for ≥6 months).




  1. A 7-year-old girl with primary nocturnal enuresis wets the bed 5 nights a week. She is due to go on a school camp in 2 weeks. What is the most appropriate short-term treatment?

Choose the correct answer

  • A) Enuresis alarm

  • B) Desmopressin

  • C) Oxybutynin

  • D) Reassure

Answer: B) Desmopressin

Explanation:

  • Desmopressin is first-line for short-term control (e.g. sleepovers, camps) or if alarm is not acceptable.



  1. After 2 complete courses of enuresis alarm and desmopressin, a 6-year-old boy still wets the bed nightly. There are no daytime symptoms. What is the next step?

Choose the correct answer

  • A) Continue alarm

  • B) Start oxybutynin

  • C) Reassure

  • D) Refer to secondary care

Answer: D) Refer to secondary care

Explanation:

  • Persistent enuresis despite two treatment courses → refer to secondary care (enuresis clinic or paediatrician).



🔑 Final MSRA Clinchers

Prematurity = major risk factor 

Re-examine unilateral undescended testis at 4-5 months 

Refer if undescended by 6 months 

Bilateral undescended + hypospadias = urgent DSD evaluation 

No role for hormonal therapy (hCG) in UK 

Orchidopexy by 12 months ideally (max 18 months) 

Cancer risk remains increased post-orchidopexy

Primary enuresis = never dry 

Secondary enuresis = dry ≥6 months then relapse 

First-line long-term = enuresis alarm 

First-line short-term / >7 years = desmopressin 

New enuresis + polydipsia + weight loss = check glucose urgently 

Constipation is a hidden cause 

Daytime symptoms = refer to secondary care

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